Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss.

Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss.

Agriculture workers have increased rates of airway and skeletal disease. Inhalant exposure to agricultural organic dust extract (ODE) induces bone deterioration in mice; yet, mechanisms underlying lung-bone crosstalk remain unclear. Because Toll-like receptor 2 (TLR2) and TLR4 are important in media...

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Bibliographic Details
Main Authors: Elizabeth Staab, Geoffrey M Thiele, Dillon Clarey, Todd A Wyatt, Debra J Romberger, Adam D Wells, Anand Dusad, Dong Wang, Lynell W Klassen, Ted R Mikuls, Michael J Duryee, Jill A Poole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4968800?pdf=render

Internet

http://europepmc.org/articles/PMC4968800?pdf=render

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