Contribution of Sequence Motif, Chromatin State, and DNA Structure Features to Predictive Models of Transcription Factor Binding in Yeast.

Transcription factor (TF) binding is determined by the presence of specific sequence motifs (SM) and chromatin accessibility, where the latter is influenced by both chromatin state (CS) and DNA structure (DS) properties. Although SM, CS, and DS have been used to predict TF binding sites, a predictiv...

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Bibliographic Details
Main Authors: Zing Tsung-Yeh Tsai, Shin-Han Shiu, Huai-Kuang Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004418