Blocking Thrombin Significantly Ameliorates Experimental Autoimmune Neuritis
Thrombin and its protease-activated receptor 1 (PAR1) are potentially important in peripheral nerve inflammatory diseases. We studied the role of thrombin and PAR1 in rat experimental autoimmune neuritis (EAN), a model of the human Guillain-Barré syndrome (GBS). EAN was induced by bovine peripheral...
Main Authors: | Efrat Shavit-Stein, Ramona Aronovich, Constantin Sylantiev, Orna Gera, Shany G. Gofrit, Joab Chapman, Amir Dori |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-01-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.01139/full |
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