Production of a cellular product consisting of monocytes stimulated with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for human use

Production of a cellular product consisting of monocytes stimulated with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for human use

Abstract Background Monocytes are myeloid cells that reside in the blood and bone marrow and respond to inflammation. At the site of inflammation, monocytes express cytokines and chemokines. Monocytes have been shown to be cytotoxic to tumor cells in the presence of pro-inflammatory cytokines such a...

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Bibliographic Details
Main Authors: Daniel S. Green, Ana T. Nunes, Kevin W. Tosh, Virginia David-Ocampo, Vicki S. Fellowes, Jiaqiang Ren, Jianjian Jin, Sue-Ellen Frodigh, Chauha Pham, Jolynn Procter, Celina Tran, Irene Ekwede, Hanh Khuu, David F. Stroncek, Steven L. Highfill, Kathryn C. Zoon, Christina M. Annunziata
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Translational Medicine
Subjects:
Cell therapy
Cellular immunotherapy
Monocytes
Interferons
Innate immunity
Online Access:http://link.springer.com/article/10.1186/s12967-019-1822-6

Internet

http://link.springer.com/article/10.1186/s12967-019-1822-6

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