Drug-excipient behavior in polymeric amorphous solid dispersions

Amorphous drug delivery systems are increasingly utilized to enhance aqueous solubility and oral bioavailability. However, they lack physical and/or chemical stability. One of the most common ways of stabilizing an amorphous form is by formulating it as an amorphous solid dispersion. This review foc...

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Bibliographic Details
Main Authors: Surikutchi Bhanu Teja, Shashank Pralhad Patil, Ganesh Shete, Sarsvatkumar Patel, Arvind Kumar Bansal
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council
Series:Journal of Excipients and Food Chemicals
Online Access:http://jefc.scholasticahq.com/article/1048-drug-excipient-behavior-in-polymeric-amorphous-solid-dispersions.pdf