A single HIV-1 cluster and a skewed immune homeostasis drive the early spread of HIV among resting CD4+ cell subsets within one month post-infection.

A single HIV-1 cluster and a skewed immune homeostasis drive the early spread of HIV among resting CD4+ cell subsets within one month post-infection.

Optimizing therapeutic strategies for an HIV cure requires better understanding the characteristics of early HIV-1 spread among resting CD4+ cells within the first month of primary HIV-1 infection (PHI). We studied the immune distribution, diversity, and inducibility of total HIV-DNA among the follo...

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Bibliographic Details
Main Authors: Charline Bacchus, Antoine Cheret, Véronique Avettand-Fenoël, Georges Nembot, Adeline Mélard, Catherine Blanc, Caroline Lascoux-Combe, Laurence Slama, Thierry Allegre, Clotilde Allavena, Yazdan Yazdanpanah, Claudine Duvivier, Christine Katlama, Cécile Goujard, Bao Chau Phung Seksik, Anne Leplatois, Jean-Michel Molina, Laurence Meyer, Brigitte Autran, Christine Rouzioux, OPTIPRIM ANRS 147 study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3653877?pdf=render

Internet

http://europepmc.org/articles/PMC3653877?pdf=render

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