Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana

Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana

Abstract Background Malaria eradication requires a combined effort involving all available control tools, and these efforts would be complemented by an effective vaccine. The antigen targets of immune responses may show polymorphisms that can undermine their recognition by immune effectors and hence...

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Bibliographic Details
Main Authors: Ebenezer A. Ofori, John K. A. Tetteh, Augustina Frimpong, Harini Ganeshan, Maria Belmonte, Bjoern Peters, Eileen Villasante, Martha Sedegah, Michael F. Ofori, Kwadwo A. Kusi
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Malaria Journal
Subjects:
Malaria
T cells
IFN-γ ELISpot
Ghana
Apical membrane antigen 1 (PfAMA1)
Online Access:https://doi.org/10.1186/s12936-021-03900-1

Internet

https://doi.org/10.1186/s12936-021-03900-1

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