Ketamine accelerates fear extinction via mTORC1 signaling

Impaired fear extinction contributes to the persistence of post-traumatic stress disorder (PTSD), and can be utilized for the study of novel therapeutic agents. Glutamate plays an important role in the formation of traumatic memories, and in the pathophysiology and treatment of PTSD, highlighting se...

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Bibliographic Details
Main Authors: Matthew J. Girgenti, Sriparna Ghosal, Dora LoPresto, Jane R. Taylor, Ronald S. Duman
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116303163