Neurexin directs partner-specific synaptic connectivity in C. elegans

Neurexin directs partner-specific synaptic connectivity in C. elegans

In neural circuits, individual neurons often make projections onto multiple postsynaptic partners. Here, we investigate molecular mechanisms by which these divergent connections are generated, using dyadic synapses in C. elegans as a model. We report that C. elegans nrx-1/neurexin directs divergent...

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Bibliographic Details
Main Authors: Alison Philbrook, Shankar Ramachandran, Christopher M Lambert, Devyn Oliver, Jeremy Florman, Mark J Alkema, Michele Lemons, Michael M Francis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
synapse
neurotransmission
AChR
nicotinic acetylcholine receptor
dendritic spine
synaptic divergence
Online Access:https://elifesciences.org/articles/35692

Internet

https://elifesciences.org/articles/35692

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