The Acetyltransferase p300/CBP-Associated Factor Is a p53 Target Gene in Breast Tumor Cells

The Acetyltransferase p300/CBP-Associated Factor Is a p53 Target Gene in Breast Tumor Cells

p300/CBP-associated factor (PCAF) is a coactivator of the tumor suppressor, p53. PCAF participates in p53's transactivation of target genes through acetylation of both bound p53 and histones within p53 target promoters. Using microarrays, we discovered that PCAF itself is induced by p53 in a p...

Full description

Bibliographic Details
Main Authors: George S. Watts, Marc M. Oshiro, Damian J. Junk, Ryan J. Wozniak, Summer J. Watterson, Frederick E. Domann, Bernard W. Futscher
Format: Article
Language:English
Published: Elsevier 2004-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Microarray
p53, PCAF
p300/CBP-associated factor
acetyltransferase
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800654

Internet

http://www.sciencedirect.com/science/article/pii/S1476558604800654

Similar Items