Zygotic Nuclear F-Actin Safeguards Embryonic Development

Zygotic Nuclear F-Actin Safeguards Embryonic Development

Summary: After fertilization, sperm and oocyte nuclei are rapidly remodeled to form swollen pronuclei (PN) in mammalian zygotes, and the proper formation and function of PN are key to producing totipotent zygotes. However, how mature PN are formed has been unclear. We find that filamentous actin (F-...

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Bibliographic Details
Main Authors: Tomomi Okuno, Wayne Yang Li, Yu Hatano, Atsushi Takasu, Yuko Sakamoto, Mari Yamamoto, Zenki Ikeda, Taiki Shindo, Matthias Plessner, Kohtaro Morita, Kazuya Matsumoto, Kazuo Yamagata, Robert Grosse, Kei Miyamoto
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
nuclear actin
pronucleus
zygote
DNA repair
transcription
chromatin
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308056

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http://www.sciencedirect.com/science/article/pii/S2211124720308056

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