Nanoparticle exposure driven circulating bioactive peptidome causes systemic inflammation and vascular dysfunction

Nanoparticle exposure driven circulating bioactive peptidome causes systemic inflammation and vascular dysfunction

Abstract Background The mechanisms driving systemic effects consequent pulmonary nanoparticle exposure remain unclear. Recent work has established the existence of an indirect process by which factors released from the lung into the circulation promote systemic inflammation and cellular dysfunction,...

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Bibliographic Details
Main Authors: Ekaterina Mostovenko, Tamara Young, Pretal P. Muldoon, Lindsey Bishop, Christopher G. Canal, Aleksandar Vucetic, Patti C. Zeidler-Erdely, Aaron Erdely, Matthew J. Campen, Andrew K. Ottens
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Particle and Fibre Toxicology
Subjects:
MWCNT
Nanomaterial
Lung
Peptidome
MMP
Mass spectrometry
Online Access:http://link.springer.com/article/10.1186/s12989-019-0304-6

Internet

http://link.springer.com/article/10.1186/s12989-019-0304-6

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