A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

The development of tools for efficient targeting of antigens to antigen presenting cells is of great importance for vaccine development. We have previously shown that fusion proteins containing antigens fused to the extra domain A from fibronectin (EDA), an endogenous TLR4 ligand, which targets anti...

Full description

Bibliographic Details
Main Authors: Laura Arribillaga, Maika Durantez, Teresa Lozano, Francesc Rudilla, Federico Rehberger, Noelia Casares, Lorea Villanueva, Marta Martinez, Marta Gorraiz, Francisco Borrás-Cuesta, Pablo Sarobe, Jesús Prieto, Juan José Lasarte
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/864720

Internet

http://dx.doi.org/10.1155/2013/864720

Similar Items