LDLR and PCSK9 Are Associated with the Presence of Antiphospholipid Antibodies and the Development of Thrombosis in aPLA Carriers.

The identification of the genetic risk factors that could discriminate non- thrombotic from thrombotic antiphospholipid antibodies (aPLA) carriers will improve prognosis of these patients. Several human studies have shown the presence of aPLAs associated with atherosclerotic plaque, which is a known...

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Bibliographic Details
Main Authors: Eguzkine Ochoa, Mikel Iriondo, Carmen Manzano, Asier Fullaondo, Irama Villar, Guillermo Ruiz-Irastorza, Ana M Zubiaga, Andone Estonba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4731066?pdf=render