Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy

In eukaryotic cells, macroautophagy is a catabolic pathway implicated in the degradation of long-lived proteins and damaged organelles. Although it has been demonstrated that macroautophagy can selectively degrade specific targets, its contribution to the basal turnover of cellular proteins has not...

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Bibliographic Details
Main Authors: Tian Zhang, Shichen Shen, Jun Qu, Sina Ghaemmaghami
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716301437