Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γ.

Human cytomegalovirus (hCMV) is a highly prevalent pathogen that, upon primary infection, establishes life-long persistence in all infected individuals. Acute hCMV infections cause a variety of diseases in humans with developmental or acquired immune deficits. In addition, persistent hCMV infection...

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Bibliographic Details
Main Authors: Theresa Knoblach, Benedikt Grandel, Jana Seiler, Michael Nevels, Christina Paulus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21533215/pdf/?tool=EBI