Streptococcus pneumoniae clonal complex 199: genetic diversity and tissue-specific virulence.

Streptococcus pneumoniae is an important cause of otitis media and invasive disease. Since introduction of the heptavalent pneumococcal conjugate vaccine, there has been an increase in replacement disease due to serotype 19A clonal complex (CC)199 isolates. The goals of this study were to 1) describ...

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Bibliographic Details
Main Authors: Jonathan C Thomas, Marisol Figueira, Kristopher P Fennie, Alison S Laufer, Yong Kong, Michael E Pichichero, Stephen I Pelton, Melinda M Pettigrew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077395?pdf=render