Streptomyces avermitilis industrial strain as cell factory for Ivermectin B1a production

Ivermectin, a kind of valuable derivatives of Avermectin, is distinct from Avermectin due to the saturated bond at C22C23 position. Combinatorial biosynthesis of Ivermectins based on Avermectins biosynthetic gene cluster (ave) has been achieved recently, while the establishment of an Ivermectin hom...

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Bibliographic Details
Main Authors: Qian Deng, Liqiongzi Xiao, Yang Liu, Lixin Zhang, Zixin Deng, Changming Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-03-01
Series:Synthetic and Systems Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X18300826