Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety- and depressive-like behavior in mice.

The aim of this study was to investigate whether conditional inactivation of the glucocorticoid receptors (GRs) in noradrenergic neurons affects animal behavior in mice. Selective ablation of GRs in the noradrenergic system was achieved using the Cre/loxP approach. We crossed transgenic mice express...

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Bibliographic Details
Main Authors: Piotr Chmielarz, Justyna Kuśmierczyk, Rosanna Parlato, Günther Schütz, Irena Nalepa, Grzegorz Kreiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3748181?pdf=render