Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

Abstract Background Preeclampsia is associated with chronic inflammation. The cholinergic anti-inflammatory pathway regulates systemic inflammation through activating α7 nicotinic acetylcholine receptors (α7nAChR) expressed in monocytes/macrophages. This study aimed to investigate the role of α7nACh...

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Bibliographic Details
Main Authors: Hongmei Xu, Qingyang Shi, Yanxiang Mo, Linlin Wu, Jishuang Gu, Ying Xu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Pregnancy and Childbirth
Subjects:
Preeclampsia
α7nAChR
Hypertension
Inflammation
NF-κB
Online Access:http://link.springer.com/article/10.1186/s12884-019-2340-5

Internet

http://link.springer.com/article/10.1186/s12884-019-2340-5

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