LRP5 and LRP6 in Wnt Signaling: Similarity and Divergence

The canonical Wnt/β-catenin signaling plays a fundamental role in regulating embryonic development, injury repair and the pathogenesis of human diseases. In vertebrates, low density lipoprotein receptor-related proteins 5 and 6 (LRP5 and LRP6), the single-pass transmembrane proteins, act as corecept...

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Bibliographic Details
Main Authors: Qian Ren, Jiongcheng Chen, Youhua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Wnt
YAP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.670960/full