Brain Pharmacokinetics and the Pharmacological Effects on Striatal Neurotransmitter Levels of Pueraria lobata Isoflavonoids in Rat

Brain Pharmacokinetics and the Pharmacological Effects on Striatal Neurotransmitter Levels of Pueraria lobata Isoflavonoids in Rat

Isoflavonoids are putatively active components of Pueraria lobata and has been demonstrated prominent neuro-protection effect against cerebrovascular disorders, hypertension or Parkinson's disease (PD). However, the molecular basis for the beneficial effect of Pueraria lobata on nervous systems...

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Bibliographic Details
Main Authors: Bingxin Xiao, Zengxian Sun, Fangrui Cao, Lisha Wang, Yonghong Liao, Xinmin Liu, Ruile Pan, Qi Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
pharmacokinetic
Pueraria lobata isoflavonoids
neurotransmitters
microdialysis
UFLC-MS/MS
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00599/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00599/full

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