The Safe Baculovirus-Based PrM/E DNA Vaccine Protected Fetuses Against Zika Virus in A129 Mice

The Safe Baculovirus-Based PrM/E DNA Vaccine Protected Fetuses Against Zika Virus in A129 Mice

The Zika virus (ZIKV) is a mosquito-borne member of the <i>Flaviviridae</i> family of enveloped RNA viruses. The correlation between viral infection and fetal microcephaly was revealed in 2015, yet we still lack a vaccine against ZIKV. Here, we present a genetic vaccine that delivers the...

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Bibliographic Details
Main Authors:  Hanul Choi, Jungmin Chun, Mina Park, Suyeon Kim, Nahyun Kim, Hee-Jung Lee, Minjee Kim, Ha Youn Shin, Yu-Kyoung Oh, Young Bong Kim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
vaccine
ZIKV
baculovirus system
arbovirus
nonreplicated viral vector
Online Access:https://www.mdpi.com/2076-393X/9/5/438

Internet

https://www.mdpi.com/2076-393X/9/5/438

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