Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes

Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes

Zinc is an essential trace element and plays critical roles in cellular integrity and biological functions. Excess copper induced both oxidative stress and endoplasmic reticulum (ER) stress in liver-derived cultured cells. Excess copper also induced impairment of autophagic flux at the step of autop...

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Bibliographic Details
Main Authors: Masashi Kusanaga, Shinji Oe, Noriyoshi Ogino, Sota Minami, Koichiro Miyagawa, Yuichi Honma, Masaru Harada
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
copper
endoplasmic reticulum stress
fatty acid
Mallory–Denk body
Wilson disease
zinc acetate
Online Access:https://www.mdpi.com/1422-0067/20/9/2192

Internet

https://www.mdpi.com/1422-0067/20/9/2192

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