Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer

Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer

Gallbladder cancer is an aggressive disease with late diagnosis and no efficacious treatment. The Hippo-Yes-associated protein 1 (YAP1) signaling pathway has emerged as a target for the development of new therapeutic interventions in cancers. However, the role of the Hippo-targeted therapy has not b...

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Bibliographic Details
Main Authors: Patricia García, Lorena Rosa, Sergio Vargas, Helga Weber, Jaime A. Espinoza, Felipe Suárez, Isabel Romero-Calvo, Nicole Elgueta, Vanessa Rivera, Bruno Nervi, Javiera Obreque, Pamela Leal, Eduardo Viñuela, Gloria Aguayo, Sabrina Muñiz, Alfredo Sagredo, Juan C. Roa, Carolina Bizama
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
gallbladder cancer
hippo pathway
molecular-targeted therapies
yap1
verteporfin
patient-derived organoids.
Online Access:https://www.mdpi.com/2072-6694/12/4/778

Internet

https://www.mdpi.com/2072-6694/12/4/778

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