Synthesis and in Vitro Antiproliferative Evaluation of Some B-norcholesteryl Benzimidazole and Benzothiazole Derivatives

Synthesis and in Vitro Antiproliferative Evaluation of Some B-norcholesteryl Benzimidazole and Benzothiazole Derivatives

Taking orostanal (a compound from a Japanese marine sponge, Stelletta hiwasaensis) as a lead compound, some novel B-norcholesteryl benzimidazole and benzothiazole derivatives were synthesized. The antiproliferative activity of the compounds against human cervical carcinoma (HeLa), human lung carcino...

Full description

Bibliographic Details
Main Authors: Jianguo Cui, Binbin Qi, Chunfang Gan, Zhipin Liu, Hu Huang, Qifu Lin, Dandan Zhao, Yanmin Huang
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Marine Drugs
Subjects:
cholesterol
B-norcholesteryl benzimidazoles
B-norcholesteryl benzothiazoles
antiproliferative activity
apoptosis
Online Access:http://www.mdpi.com/1660-3397/13/4/2488

Internet

http://www.mdpi.com/1660-3397/13/4/2488

Similar Items