Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments.

Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry. Therefore, an efficient vaccination that elicits protective and neutralizing antibodies against the viral hemagglutinin (HA...

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Bibliographic Details
Main Authors: Ahmed Mostafa, Pumaree Kanrai, Henning Petersen, Sherif Ibrahim, Silke Rautenschlein, Stephan Pleschka
Format: Article
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4304806?pdf=render