In vitro anti-malarial efficacy of chalcones: cytotoxicity profile, mechanism of action and their effect on erythrocytes

Abstract Background Malaria extensively leads to mortality and morbidity in endemic regions, and the emergence of drug resistant parasites is alarming. Plant derived synthetic pharmaceutical compounds are found to be a foremost research to obtain diverse range of potent leads. Amongst them, the chal...

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Bibliographic Details
Main Authors: Shweta Sinha, Daniela I. Batovska, Bikash Medhi, B. D. Radotra, Ashish Bhalla, Nadezhda Markova, Rakesh Sehgal
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Malaria Journal
Subjects:
Online Access:https://doi.org/10.1186/s12936-019-3060-z