Activation of ERK and Akt Signaling in Focal Cerebral Ischemia: Modulation by TGF-α and Involvement of NMDA Receptor
Cerebral ischemia activates ERK and Akt pathways. We studied whether these activations were affected by treatment with the protective growth factor transforming growth factor-α (TGF-α), and whether they were mediated through N-methyl d-aspartate (NMDA) receptors. The middle cerebral artery was occlu...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2002-12-01
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| Series: | Neurobiology of Disease |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S096999610290553X |