Macrophage Lysophosphatidylcholine Acyltransferase 3 Deficiency-Mediated Inflammation Is Not Sufficient to Induce Atherosclerosis in a Mouse Model

Macrophage Lysophosphatidylcholine Acyltransferase 3 Deficiency-Mediated Inflammation Is Not Sufficient to Induce Atherosclerosis in a Mouse Model

Mammalian cell membrane phosphatidylcholines (PCs), the major phospholipids, exhibit diversity which is controlled by Lands' cycle or PC remodeling pathway. Lysophosphatidylcholine acyltransferase (LPCAT) is one of the major players in the pathway and plays an important role in maintaining cell...

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Bibliographic Details
Main Authors: Hui Jiang, Zhiqiang Li, Chongmin Huan, Xian-Cheng Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
lysophosphatidylcholine acyltransferase 3 (LPCAT3)
phosphatidylcholine remodeling
macrophage Lpcat3 gene knockout mice
inflammation
atherosclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00192/full

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https://www.frontiersin.org/article/10.3389/fcvm.2018.00192/full

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