Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.

Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.

Burkitt's lymphoma (BL), an EBV-associated tumour, occurs at high incidence in populations where malaria is holoendemic. Previous studies in one such population suggested that acute P.falciparum infection impairs EBV-specific T-cell surveillance, allowing expansion of EBV infected B-cells from...

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Bibliographic Details
Main Authors: Shamanthi Jayasooriya, Andrew Hislop, Yanchun Peng, Debbie Croom-Carter, Ya Jankey, Andrew Bell, Tao Dong, Sarah Rowland-Jones, Alan Rickinson, Michael Walther, Hilton Whittle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3275582?pdf=render

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http://europepmc.org/articles/PMC3275582?pdf=render

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