Multiplex Matrix Metalloproteinases Analysis in the Cerebrospinal Fluid Reveals Potential Specific Patterns in Multiple Sclerosis Patients

Multiplex Matrix Metalloproteinases Analysis in the Cerebrospinal Fluid Reveals Potential Specific Patterns in Multiple Sclerosis Patients

Background: Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of many neurological diseases, including multiple sclerosis (MS).Objective: To search the level of MMPs in the cerebrospinal fluid...

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Bibliographic Details
Main Authors: Massimiliano Castellazzi, Daniela Ligi, Elena Contaldi, Davide Quartana, Mattia Fonderico, Luca Borgatti, Tiziana Bellini, Alessandro Trentini, Enrico Granieri, Enrico Fainardi, Ferdinando Mannello, Maura Pugliatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
cerebrospinal fluid
matrix metalloproteinases
sex
aging
blood-brain-barrier
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01080/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.01080/full

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