Trajectories of Brain Lactate and Re-visited Oxygen-Glucose Index Calculations Do Not Support Elevated Non-oxidative Metabolism of Glucose Across Childhood

Trajectories of Brain Lactate and Re-visited Oxygen-Glucose Index Calculations Do Not Support Elevated Non-oxidative Metabolism of Glucose Across Childhood

Brain growth across childhood is a dynamic process associated with specific energy requirements. A disproportionately higher rate of glucose utilization (CMRglucose) compared with oxygen consumption (CMRO2) was documented in children's brain and suggestive of non-oxidative metabolism of glucose...

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Bibliographic Details
Main Authors: Helene Benveniste, Gerald Dienel, Zvi Jacob, Hedok Lee, Rany Makaryus, Albert Gjedde, Fahmeed Hyder, Douglas L. Rothman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Neuroscience
Subjects:
non-oxidative metabolism
aerobic glycolysis
brain
child
development
lactate
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00631/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00631/full

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