Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

Summary: Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood. Using genetic loss and gain-of-function analyses in vivo, we show that the conserved MAP3K13 (also known as l...

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Bibliographic Details
Main Authors: Meifan Chen, Cédric G. Geoffroy, Jessica M. Meves, Aarti Narang, Yunbo Li, Mallorie T. Nguyen, Vung S. Khai, Xiangmei Kong, Christopher L. Steinke, Krislyn I. Carolino, Lucie Elzière, Mark P. Goldberg, Yishi Jin, Binhai Zheng
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718303127

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http://www.sciencedirect.com/science/article/pii/S2211124718303127

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