Strand Displacement Activity of PrimPol

Strand Displacement Activity of PrimPol

Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn<sup>2+</sup> ions and accessory replicative prote...

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Bibliographic Details
Main Authors: Elizaveta O. Boldinova, Ekaterina A. Belousova, Diana I. Gagarinskaya, Ekaterina A. Maltseva, Svetlana N. Khodyreva, Olga I. Lavrik, Alena V. Makarova
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
PrimPol
strand displacement
RPA
PolDIP2
FEN1
Online Access:https://www.mdpi.com/1422-0067/21/23/9027

Internet

https://www.mdpi.com/1422-0067/21/23/9027

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