Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB

Leishmania is the aethiological agent responsible for the visceral leishmaniasis, a serious parasite-borne disease widely spread all over the World. The emergence of resistant strains makes classical treatments less effective; therefore, new and better drugs are necessary. Naphthoquinones are intere...

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Main Authors: Yolanda Pérez-Pertejo, José M. Escudero-Martínez, Rosa M. Reguera, Rafael Balaña-Fouce, Pablo A. García, Pablo G. Jambrina, Arturo San Feliciano, María-Ángeles Castro
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320719301095