Imatinib-induced changes in the expression profile of microRNA in the plasma and heart of mice—A comparison with doxorubicin

Cardiotoxicity is a serious adverse reaction to cancer chemotherapy and may lead to critical heart damage. Imatinib mesylate (IMB), a selective tyrosine kinase inhibitor, is sometimes accompanied by severe cardiovascular complications. To minimize risk, early biomarkers of such complications are of...

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Bibliographic Details
Main Authors: Barbora Hanousková, Mikuláš Skála, Veronika Brynychová, Tomáš Zárybnický, Veronika Skarková, Petra Kazimírová, Andrea Vernerová, Pavel Souček, Lenka Skálová, Radek Pudil, Petra Matoušková
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219302860