DRPnet: automated particle picking in cryo-electron micrographs using deep regression

DRPnet: automated particle picking in cryo-electron micrographs using deep regression

Abstract Background Identification and selection of protein particles in cryo-electron micrographs is an important step in single particle analysis. In this study, we developed a deep learning-based particle picking network to automatically detect particle centers from cryoEM micrographs. This is a...

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Bibliographic Details
Main Authors: Nguyen Phuoc Nguyen, Ilker Ersoy, Jacob Gotberg, Filiz Bunyak, Tommi A. White
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Bioinformatics
Subjects:
Convolutional neural network
Regression
Deep learning
Electron microscopy
Image segmentation
Particle picking
Online Access:https://doi.org/10.1186/s12859-020-03948-x

Internet

https://doi.org/10.1186/s12859-020-03948-x

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