A novel pH-sensitive carrier for the delivery of antitumor drugs: histidine-modified auricularia auricular polysaccharide nano-micelles

Abstract The study was aimed to design a novel pH-sensitive carrier to deliver antitumor drugs to increase treatment efficiency. Histidine (His)was used to modify auricularia auricular polysaccharide (AAP) by esterification. Proton nuclear magnetic resonance spectrometry was developed to characteriz...

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Bibliographic Details
Main Authors: Yingying Wang, Pingfei Li, Fen Chen, Lianqun Jia, Qihao Xu, Xiumei Gai, Yibin Yu, Yan Di, Zhihong Zhu, Yanyao Liang, Mengqi Liu, Weisan Pan, Xinggang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04428-8