A novel pH-sensitive carrier for the delivery of antitumor drugs: histidine-modified auricularia auricular polysaccharide nano-micelles
Abstract The study was aimed to design a novel pH-sensitive carrier to deliver antitumor drugs to increase treatment efficiency. Histidine (His)was used to modify auricularia auricular polysaccharide (AAP) by esterification. Proton nuclear magnetic resonance spectrometry was developed to characteriz...
Main Authors: | Yingying Wang, Pingfei Li, Fen Chen, Lianqun Jia, Qihao Xu, Xiumei Gai, Yibin Yu, Yan Di, Zhihong Zhu, Yanyao Liang, Mengqi Liu, Weisan Pan, Xinggang Yang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-04428-8 |
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