Tumor development, growth characteristics and spectrum of genetic aberrations in the TH-MYCN mouse model of neuroblastoma.

Tumor development, growth characteristics and spectrum of genetic aberrations in the TH-MYCN mouse model of neuroblastoma.

<h4>Background</h4>The TH-MYCN transgenic neuroblastoma model, with targeted MYCN expression to the developing neural crest, has been used to study neuroblastoma development and evaluate novel targeted tumor therapies.<h4>Methods</h4>We followed tumor development in 395 TH-MY...

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Bibliographic Details
Main Authors: Agnes Rasmuson, Lova Segerström, Maria Nethander, Jennie Finnman, Lotta H M Elfman, Niloufar Javanmardi, Staffan Nilsson, John Inge Johnsen, Tommy Martinsson, Per Kogner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284678/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284678/?tool=EBI

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