Cytokine-mediated inflammation mediates painful neuropathy from metabolic syndrome.

Painful neuropathy (PN) is a prevalent condition in patients with metabolic syndrome (MetS). However, the pathogenic mechanisms of metabolic syndrome-associated painful neuropathy (MetSPN) remain unclear. In the current study, high-fat-fed mice (HF mice) were used to study MetSPN. HF mice developed...

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Bibliographic Details
Main Authors: Can Zhang, Joseph Ward, Jacqueline R Dauch, Rudolph E Tanzi, Hsinlin T Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5800683?pdf=render