Pleiotrophin commits human bone marrow mesenchymal stromal cells towards hypertrophy during chondrogenesis.

Pleiotrophin (PTN) is a growth factor present in the extracellular matrix of the growth plate during bone development and in the callus during bone healing. Bone healing is a complicated process that recapitulates endochondral bone development and involves many cell types. Among those cells, mesench...

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Bibliographic Details
Main Authors: Thibault Bouderlique, Emilie Henault, Angelique Lebouvier, Guilhem Frescaline, Phillipe Bierling, Helene Rouard, José Courty, Patricia Albanese, Nathalie Chevallier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3917886?pdf=render