Pleiotrophin commits human bone marrow mesenchymal stromal cells towards hypertrophy during chondrogenesis.
Pleiotrophin (PTN) is a growth factor present in the extracellular matrix of the growth plate during bone development and in the callus during bone healing. Bone healing is a complicated process that recapitulates endochondral bone development and involves many cell types. Among those cells, mesench...
Main Authors: | Thibault Bouderlique, Emilie Henault, Angelique Lebouvier, Guilhem Frescaline, Phillipe Bierling, Helene Rouard, José Courty, Patricia Albanese, Nathalie Chevallier |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3917886?pdf=render |
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