Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease.

Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease.

3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger, provides neuroprotection in stroke models and patients. In this study, we investigated its neuroprotective effects in a chronic rotenone rat model for Parkinson's disease. Here we showed that a five-week treat...

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Bibliographic Details
Main Authors: Nian Xiong, Jing Xiong, Ghanshyam Khare, Chunnuan Chen, Jinsha Huang, Ying Zhao, Zhentao Zhang, Xian Qiao, Yuan Feng, Harrish Reesaul, Yongxue Zhang, Shenggang Sun, Zhicheng Lin, Tao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108992?pdf=render

Internet

http://europepmc.org/articles/PMC3108992?pdf=render

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