The human C1q globular domain: Structure and recognition of non immune self ligands

C1q, the ligand binding unit of the C1 complex of complement, is a pattern recognition molecule with the unique ability to sense an amazing variety of targets, including a number of altered structures from self, such as apoptotic cells. The three-dimensional structure of its C-terminal globular dom...

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Bibliographic Details
Main Authors: Christine eGaboriaud, Philippe eFrachet, Nicole eThielens, Gerard eArlaud
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Immunology
Subjects:
c1q
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00092/full