Prognostic genetic markers in malignant gliomas

Glioblastomas are the most frequent and malignant brain tumors in adults. Surgical cure is virtually impossible and despite of radiation and chemotherapy the clinical course is very poor. Epigenetic silencing of MGMT has been associated with a better response to temozolomide-chemotherapy. We previo...

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Bibliographic Details
Main Authors: Ralf Ketter, Silke Wemmert, Stefan Linsler, Wolf-Ingo Steudel, Steffi Urbschat
Format: Article
Language:English
Published: London Academic Publishing 2010-12-01
Series:Romanian Neurosurgery
Subjects:
Online Access:https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/519