Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

The host immune response effecting on biomaterials is critical to determine implant fates and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes (Exos) contain multiple biosignal molecules and have been demonstrated to exhibit immunomodulatory functions. Herein, we develop a...

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Bibliographic Details
Main Authors: Lei Fan, Pengfei Guan, Cairong Xiao, Huiquan Wen, Qiyou Wang, Can Liu, Yian Luo, Limin Ma, Guoxin Tan, Peng Yu, Lei Zhou, Chengyun Ning
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-09-01
Series:Bioactive Materials
Subjects:
Osteoimmunology
Macrophages polarization
Polyetheretherketone
BMSC-Derived exosomes
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000578

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http://www.sciencedirect.com/science/article/pii/S2452199X21000578

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