Machine Learning Driven Profiling of Cerebrospinal Fluid Core Biomarkers in Alzheimer’s Disease and Other Neurological Disorders

Machine Learning Driven Profiling of Cerebrospinal Fluid Core Biomarkers in Alzheimer’s Disease and Other Neurological Disorders

Amyloid-beta (Aβ) 42/40 ratio, tau phosphorylated at threonine-181 (p-tau), and total-tau (t-tau) are considered core biomarkers for the diagnosis of Alzheimer’s disease (AD). The use of fully automated biomarker assays has been shown to reduce the intra- and inter-laboratory variability, which is a...

Full description

Bibliographic Details
Main Authors: Giovanni Bellomo, Antonio Indaco, Davide Chiasserini, Emanuela Maderna, Federico Paolini Paoletti, Lorenzo Gaetani, Silvia Paciotti, Maya Petricciuolo, Fabrizio Tagliavini, Giorgio Giaccone, Lucilla Parnetti, Giuseppe Di Fede
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
biomarkers
dementia
cerebrospinal fluid
amyloid-beta
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.647783/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.647783/full

Similar Items