Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes.

Helicobacter pylori infection is a risk factor for the development of gastric adenocarcinoma, a disease that has a high incidence in East Asia. Genes that are highly divergent in East Asian H. pylori strains compared to non-Asian strains are predicted to encode proteins that differ in functional act...

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Bibliographic Details
Main Authors: Stacy S Duncan, Pieter L Valk, Mark S McClain, Carrie L Shaffer, Jason A Metcalf, Seth R Bordenstein, Timothy L Cover
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561388?pdf=render